Associate Scientist, Medicinal Chemistry/Radiochemistry

Alpha-9 Theranostics is a clinical stage, radiopharmaceutical company developing imaging and therapeutic molecules for solid and hematologic malignancies. We have multiple molecules that are headed into clinic within the next few years, and a robust pipeline of additional targets for future development. Using proprietary technology and the Company’s expertise, these differentiated molecules have the potential to meaningfully extend patients’ lives with favorable safety profiles. Alpha-9 was founded by researchers from the University of British Columbia and BC Cancer, with the goal of improving the lives of patients affected by metastatic cancers.

Position Description:

Alpha-9 is seeking Associate Scientists to join our Medicinal Chemistry/Radiochemistry group. The ideal candidate will have hands-on experience in synthetic organic chemistry, including in the synthesis, isolation and purification of either small molecules, peptides or peptidomimetics. This person will be responsible synthesizing peptides/peptidomimetic building blocks and precursors for radiopharmaceutical product candidates. Experience with solid-phase peptide synthesis and radiolabeling in the discovery setting is a plus, but training would be provided if needed.

We are an early-stage company, so you will have the opportunity to participate cross-functionally and contribute to the build-out and set-up of new laboratory facilities. The ideal candidate will have multi-tasking ability and a desire to strive in a fast-paced environment.

Some specific duties and tasks include, but are not limited to, the following:

• Synthesis of peptides/peptidomimetics or small molecule-based building blocks and drug substances for radiopharmaceutical development
• Compound characterization employing LC-MS/MS, GC-MS, HPLC and NMR
• Active participation in discussions and present results in team meetings
• Key participant in the writing of patent applications
• Contribution to build-out and set up of a new laboratory facility
• Maintenance of clear and accurate lab records, adherence to all safety and compliance requirements
• Lab maintenance and support of ordering and receipt of needed supplies

Qualifications:

• BS or MS degree in Chemistry or related area with 2-5+ years of related industrial experience
• Solid understanding and practical experience in synthetic organic chemistry
• Solid experience in modern synthetic and analytical techniques
• Experience with solid-phase peptide synthesis preferred, but not required
• Experience in radiopharmaceutical discovery preferred, but not required
• Excellent observational, organizational, data management, and documentation skills
• A team player with excellent interpersonal skills and a strong passion for the discovery of targeted therapies in a fast-paced start-up environment

What’s in it for you:

• Competitive Salary, Bonus, and Equity
• Full extended health and dental benefits
• Commuter Reimbursement
• Group Registered Retirement Savings Plan with 5% employer matching
• 20 vacation days
• 17 Holidays
• 5 Sick Days
• Long Term Disability
• Life Insurance
• Impactful rewarding work

Schedule:

• Full Time Permanent

Location: Vancouver

Job Type: Full-time

Benefits:

• Commuter benefits
• Dental care
• Disability insurance
• Employee assistance program
• Extended health care
• Life insurance
• Paid time off
• RRSP match
• Stock options
• Vision care

Schedule:

• Monday to Friday

Supplemental pay types:

• Bonus pay

Ability to commute/relocate:

• Vancouver, BC V5Y 1T5: reliably commute or plan to relocate before starting work (required)

Application question(s):

• We require our employees to be fully vaccinated against COVID and provide proof of vaccination. If hired, can you comply with this requirement?

Education:

• Bachelor's Degree (required)

Experience:

• Laboratory: 2 years (required)

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